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Tools & Data

Tools & Data

Explore polygenic risk score evaluations, research software, practical guides, and archived PRSweb releases.

Featured resource

Public collection

PRSweb Research Portals

Compare published polygenic risk scores evaluated in the Michigan Genomics Initiative (MGI) and UK Biobank, and explore phenome-wide associations and downloadable files.

Useful for: comparing candidate scores, examining performance and phenome-wide results, and finding release-specific downloads.

View PRSweb releases Open the portals
The public PRSweb landing page with trait search and cards for Skin Cancer PRSweb, Cancer PRSweb, and ExPRSweb.
The public PRSweb landing page, captured September 2026.

Open tools and guides

PheWAS software

Public

phewasFlow

An R package for reproducible phenome-wide association studies in both directions, with local and cluster workflows, multiple-testing correction, and Manhattan and volcano plots.

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Research computing guide

Supported

Fritsche Lab SLURM Playbook

The SLURM Playbook covers submitting and monitoring CPU jobs and job arrays on U-M clusters, diagnosing failures, and rerunning only failed tasks.

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Research practice guide

Teaching guide

Practical GenAI Coding Guide

An eight-step workflow for AI-assisted research code, covering planning, prompting, review, testing, version control, and documentation.

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Archived PRSweb releases

These portals preserve the versions described in their papers. Their score files, mappings, and results remain available to help researchers reproduce or extend the published analyses.

Polygenic risk archive

Archived release

Cancer PRSweb

The archived June 2020 release reports evaluations of cancer polygenic risk scores in the Michigan Genomics Initiative (MGI) and UK Biobank.

More than 305 filtered scores across more than 39 retained traits.

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Polygenic risk archive

Archived release

ExPRSweb

The archived November 2021 release reports evaluations of polygenic risk scores for common health-related exposures.

More than 336 filtered scores across more than 28 retained traits.

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Polygenic risk archive

Archived release

Skin Cancer PRSweb

The original June 2019 release evaluates 20 polygenic risk scores for melanoma, basal cell carcinoma, squamous cell carcinoma, and overall skin cancer.

Twenty scores across four traits in the June 2019 release.

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Additional tool

  • MapDbSNP adds versioned genomic positions to files containing dbSNP identifiers. See the repository README for setup and usage instructions.