From the lab
News
Research stories, talks, funding announcements, and resource updates.
Read about research on genetic risk, treatment outcomes, and mental health, along with the collaborations and resources behind the work.
Stories, talks, and milestones
· Funding
Studying depressive symptoms after surgery
A two-year project aims to identify patients who may need additional support for depressive symptoms after surgery.
· Research story
U-M researchers aim to shorten the path to effective mental health care
COMPASS participants contribute repeated reports, genetic samples, and health record data to study why mental health treatment responses differ.
· Research story
Comparing cancer immunotherapy outcomes in Black and white patients
A study using Veterans Health Administration records compared survival and immune-related adverse events in Black and white patients receiving cancer immunotherapy.
· Video
MGI 2024: Lars Fritsche
A U-M symposium talk by Lars Fritsche examines a decade of genetics research linked to electronic health records, with examples from PheWeb and PRSweb.
· Funding
U-M announces NIMH-backed COMPASS precision mental health grant
A $17.9 million NIMH award supports COMPASS, a collaboration studying differences in mental health treatment response.
· Research story
Comparing methods for evaluating COVID-19 booster effectiveness
A comparison of observational methods examined how study design and analysis choices affect estimates of COVID-19 booster effectiveness.
· Research story
Estimating the global prevalence of long COVID
A systematic review and meta-analysis combined 50 studies to compare long COVID prevalence across regions, follow-up periods, and hospitalization status.
· Research story
Evaluating cancer polygenic risk scores across ancestry groups
Cancer polygenic risk scores were evaluated across ancestry groups in UK Biobank, highlighting the need for more diverse genetic studies.
· Research resource
Democratizing genetic data for cancer research
Cancer PRSweb provides archived comparisons of cancer polygenic risk scores in the Michigan Genomics Initiative and UK Biobank.
· Research story
Genetic risk for abdominal aortic aneurysm
A genetic study in the Million Veteran Program identified regions associated with abdominal aortic aneurysm and evaluated a polygenic risk score.
· Research story
Max Salvatore on COVID-19 modeling in India
Max Salvatore reflects on his cancer research experience and subsequent work modeling COVID-19 in India.
· Funding
Eye expert leads research to better predict blindness in patients
An international collaboration combines clinical measures, retinal imaging, genetics, and machine learning to study progression of age-related macular degeneration.
· Research story
Evaluating cancer polygenic risk scores in the Michigan Genomics Initiative
Cancer polygenic risk scores were associated with diagnoses of cancers and related conditions in the Michigan Genomics Initiative.
· Research story
Common and rare genetic variants in age-related macular degeneration
An international study of about 43,000 people identified common and rare genetic variants associated with age-related macular degeneration.
